Researchers investigating the role of progranulin in cancer progression have previously identified the signaling receptor EphA2 as critical in tumor establishment and a potential target to enhance the effectiveness of chemotherapy. While the exact molecular mechanisms of action are still not well understood, the…
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Some patients develop aggressive blood cancers years after receiving chemotherapy or radiotherapy for a previous cancer. These conditions, known as therapy-related myeloid neoplasms (t-MN), are currently classified mainly according to a patient's treatment history, even though their clinical course can vary…
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