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Онкология
FDA approval opens new chapter in pancreatic cancer treatment
For decades, a diagnosis of metastatic pancreatic cancer left patients and physicians facing the same harsh reality: limited options, difficult treatments and too little time. Now, a pill tested in a global clinical trial may begin to change that.
Онкология
Multicenter study suggests early rasburicase prevents kidney failure and death in tumor lysis syndrome
Tumor lysis syndrome (TLS) is a life-threatening emergency that occurs when large numbers of cancer cells break down rapidly, releasing substances such as uric acid into the bloodstream that can damage the kidneys and cause serious complications.
Онкология
Genetic ancestry has significant link to colorectal cancer risk
Genetic ancestry may have significant associations with colorectal cancer incidence and age-specific risk. An evaluation of more than 300,000 individuals with whole genome sequencing showed that individuals with European ancestry had greater overall odds of developing colorectal cancer, but other lineages, including…
Онкология
Out of sync: How competing demands shape the cancer patient experience
Scientists are making progress in developing new cancer treatments, but a patient's experience with cancer is shaped by more than medicine. A new sociological study finds that conflicting medical, work and family timelines compound inequality, draining resources and displacing goals for even the most advantaged…
Онкология
Pre-cancerous blood cells may fuel disease risk by prematurely aging the bone marrow
Precancerous blood cells can actively reshape their surroundings, prematurely aging cells in the bone marrow to create conditions that favor their own growth and potentially increase the risk of blood cancer, according to a new study by researchers at The Jackson Laboratory (JAX).
Онкология
Researchers develop scalable method to generate key immune cells for cancer therapy
Researchers at the Center for Regenerative Medicine (CReM) at Boston Medical Center (BMC) and Boston University (BU) have developed a scalable method for generating CD4+ helper T cells from induced pluripotent stem cells (iPSCs), overcoming a longstanding challenge in the development of stem cell-based…
Онкология
An 'undruggable' cancer target meets an RNA-based strategy to curb tumor growth
Researchers at Umeå University have developed a strategy to slow the growth of tumor cells. By targeting the genetic instructions that control the production of a key cancer-related protein, they were able to inhibit tumor cell growth. The findings are published in the Proceedings of the National Academy of Sciences.
Онкология
Unexpected discovery reveals mechanism behind brain tumor development
When researchers at Lund University investigated how UM171, a molecule used to make blood stem cells multiply, works, they made an unexpected connection. The results provide new insights into how one of the most common malignant brain tumors in children could be treated in the future. Their research is published in…