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Онкология

Liver tumors form without detectable driver mutations in mice, revealing epigenetic route

Cancers can develop through epigenetic pathways even without driver gene mutations (DGMs), according to a study from Science Tokyo. Researchers uncovered the YAP1–TEAD–TET1 axis, which triggers DNA demethylation and activates multiple oncogenes in hepatocellular carcinoma. Suppressing TET1 reduced tumor formation in…

Онкология

Research finds young adult cancer survivors face gaps in long-term care

Young adult cancer survivors face gaps in follow-up care caused by factors including geographic mobility and insurance changes, according to an analysis by UTHealth Houston researchers. While most young adults are navigating college, the workforce or relationships, survivors face that and more as they learn to manage…

Онкология

Oxford scientists discover how viruses build themselves without a blueprint

Scientists have captured virus-like particles assembling themselves step by step, revealing how a surprisingly simple process of trial and error produces complex structures with remarkable precision. The discovery uncovers a crucial molecular turning point that speeds up assembly and could lead to new ways to disrupt…