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Онкология

Ancient viral remnants in our genome may help predict response to chemotherapy

In a new study, researchers from King's College London trained AI models on multiple types of clinical and biological data to determine whether they could predict which patients with acute myeloid leukemia (AML) would respond to chemotherapy. They found that behavior related to ancient viral sequences in the genome…

Онкология

RNA creates a self-destruct switch for cellular machinery linked to leukemia

Cells have all kinds of intricate machinery to control genes, switching them on and off at the right times and under the right conditions. Components of this machinery include chromatin-modifying complexes, groups of proteins that manage how tightly DNA is packaged in the nucleus and control how accessible it is for…