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Онкология

Tumor mutations and immune activity may reveal who benefits from investigational lymphoma drug

Researchers at the University of Tsukuba conducted a physician-initiated phase 2 clinical trial of dasatinib in patients with relapsed or refractory T-follicular helper cell lymphoma (TFHL), an aggressive and difficult-to-treat blood cancer. The study identified genetic alterations and features of the immune…

Онкология

Residential fine particulate matter linked to minimal residual disease in pediatric leukemia

For pediatric patients with high-risk B-cell acute lymphoblastic leukemia (B-ALL), residential fine particulate matter (PM₂.₅) concentrations during induction therapy are associated with positive end-of-induction (EOI) minimal residual disease (MRD), according to a study published in JNCI Cancer Spectrum.

Онкология

Lab-on-a-chip predicts which cancer treatments may work for pediatric acute lymphoblastic leukemia

More than 120,000 people in the U.S. are living with acute lymphoblastic leukemia (ALL), and 6,000 new cases are diagnosed each year. Of those, more than 3,500 will be in children. Responsible for 75% of all pediatric leukemia diagnoses, ALL is a rapid-onset blood cancer, preventing the body from producing mature…

Онкология

New leukemia drug suppresses cancer-driving protein more strongly than existing treatments within one week

A more effective and better-tolerated treatment for chronic myeloid leukemia (CML) could improve quality of life for people living with the disease. A new study led by Adelaide University and the South Australian Health and Medical Research Institute (SAHMRI) has provided the first direct evidence that a targeted…