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Онкология

An alternative to bone marrow sampling: Children with sarcomas may be spared a painful procedure

Rhabdomyosarcomas are a rare form of cancer; however, the disease is responsible for about 60% of all soft-tissue sarcomas in children. Rhabdomyosarcomas are aberrant, malignant forms of muscle tissue. Early detection of bone marrow infiltration by tumor cells is crucial when planning treatment.

Онкология

Blocking cellular 'freecycling' may slow bone marrow scarring in myelofibrosis

In a new study published in Nature Communications, Boston Children's Hospital researchers identified a new target responsible for scar formation in the bone marrow of patients with a type of blood cancer known as myelofibrosis. Combining traditional myelofibrosis therapy with drugs that block scar formation may be a…

Онкология

First-in-human pilot trial improves stem cell collection and delivery for sickle cell gene therapy

Patients with sickle cell disease are often hesitant to undergo transformative gene therapy—the current lengthy process requires multiple hospital visits to collect enough stem cells. Researchers from Boston Children's Hospital have helped smooth the road to gene therapy with a new approach that collects enough of the…