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Онкология

Mitochondrial RNA escape may explain how chronic immune signaling helps tumors grow

Cancer biology—and, in turn, cancer treatment—have come a long way in the last few decades. Most people recognize this progress in breakthroughs like immunotherapy, a treatment strategy first deployed in 2011 that leverages the body's own immune cells to fight cancer. It has revolutionized the treatment landscape…

Онкология

RNA creates a self-destruct switch for cellular machinery linked to leukemia

Cells have all kinds of intricate machinery to control genes, switching them on and off at the right times and under the right conditions. Components of this machinery include chromatin-modifying complexes, groups of proteins that manage how tightly DNA is packaged in the nucleus and control how accessible it is for…