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Онкология

Neighborhood conditions linked to childhood cancer survivors' long-term health

Survivors of childhood cancer can make lifestyle changes to reduce later-in-life chronic health conditions, such as diabetes and heart disease. Still, some survivors report local environmental barriers to taking these actions. According to a new study from St. Jude Children's Research Hospital scientists, survivors…

Онкология

‘Unknown territory’: How can prediction markets affect drug trials?

Prediction marketplaces are taking their first steps into the pharmaceutical field — a move that some experts say may threaten the integrity of clinical trials. Prediction markets are platforms where users buy and sell shares on the future outcomes of events across a variety of subjects, like entertainment, sports…

Онкология

Reversible genetic switches could give cancer immunotherapy more precise control

A genetic switch that activates immune cells as they fight tumors: this is the new strategy developed by an international research team coordinated by Velia Siciliano at the Istituto Italiano di Tecnologia (IIT—Italian Institute of Technology) in Naples and described in the journal Nature Communications. The study…

Онкология

Cancer-linked protein needs a partner to activate silent DNA, fruit fly experiments reveal

In Ewing sarcoma, an abnormal protein formed by the fusion of two genes can activate repetitive DNA regions that normally remain silenced and turn them into gene regulatory elements. This mechanism contributes significantly to the development of this tumor and is one of its best-studied molecular hallmarks.