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Онкология

Thymus health may impact mortality, cancer outcomes in adults

When Hugo Aerts, PhD, started asking colleagues whether the thymus could play a role in determining which patients with cancer would respond to immunotherapy about 4 years ago, the responses were overwhelmingly dismissive. “It’s irrelevant,” they told him. “[The thymus is] important in kids. Afterwards, it doesn’t…

Онкология

Heavily immunosuppressed patients undergoing anticancer immunotherapy face increased risk of severe infections

Immune checkpoint inhibitors (ICIs) can promote antitumor responses but can also cause adverse effects that require treatment with immunosuppressive drugs. A new retrospective study by Mass General Brigham Cancer Institute investigators found that patients who received ICIs and multiple immunosuppressive therapies…