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Онкология

Targeted drug significantly delays advanced breast cancer progression but increases toxicity, phase III trial reports

In a global phase 1 trial, trastuzumab rezetecan showed promising signs of fighting ERBB2-low metastatic breast cancer in patients who had already undergone extensive treatment. Also known as HER2-low breast cancer, this subtype is characterized by low levels of HER2, a growth factor protein that can still be targeted…

Онкология

Exploring the potential of immunotherapy in early-stage triple-negative breast cancer

Triple-negative breast cancers, which are more frequently diagnosed in younger women, are a subtype of breast tumor characterized by the absence of hormone receptors and HER2 overexpression. As a result, they do not respond to hormone therapy or HER2-targeted treatments. Their prognosis is generally less favorable…

Онкология

Breast Cancer Index influences extended endocrine therapy choice

Results from Breast Cancer Index testing prompted more than 40% of physicians to change extended endocrine therapy decisions for women with early-stage, hormone receptor-positive breast cancer. An analysis of nearly 3,000 patients found the number of physicians who reported high confidence in their decision-making…